Human CEND1 Recombinant Protein (RPPB3143)
- SKU:
- RPPB3143
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- CEND1
- Synonyms:
- Cell Cycle Exit And Neuronal Differentiation 1
- BM88
- BM88Antigen
- Cell Cycle Exit And Neuronal Differentiation Protein 1
- Source:
- Escherichia Coli
- Uniprot:
- Q8N111
Description
| Product Name: | Human CEND1 Recombinant Protein |
| Product Code: | RPPB3143 |
| Size: | 20µg |
| Species: | Human |
| Target: | CEND1 |
| Synonyms: | Cell Cycle Exit And Neuronal Differentiation 1, BM88, BM88Antigen, Cell Cycle Exit And Neuronal Differentiation Protein 1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CEND1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greaterthan 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMESRGKS ASSPKPDTKV PQVTTEAKVP PAADGKAPLT KPSKKEAPAEKQQPPAAPTT APAKKTSAKA DPALLNNHSN LKPAPTVPSS PDATPEPKGP GDGAEEDEAA SGGPGGRGPWSCENFNPL |
CellCycle Exit And Neuronal Differentiation 1, also known as CEND1, is aneuron-specific protein. CEND1 take partin cell cycle control and neuronal differentiation mechanisms during neonatalSVZ neurogenesis and turn out to be crucial for the transition from neuroblaststo mature neurons when reaching high levels. The similar protein in pigenhances neuroblastoma cell differentiation in vitro and involved in neuronaldifferentiation in vivo. Multiple pseudogenes have been reported for this gene.The disease neuroblastoma has been associated with CEND1.
CEND1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 148 amino acids (1-125 a.a) and having a molecular mass of 15.0kDa (molecular size on SDS-PAGE will appear higher).CEND1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Involved in neuronal differentiation. |
| NCBI Summary: | The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8N111 |
| NCBI GenInfo Identifier: | 30795225 |
| NCBI Gene ID: | 51286 |
| NCBI Accession: | NP_057648.2 |
| UniProt Secondary Accession: | Q8N111,Q9NYM6, |
| UniProt Related Accession: | Q8N111 |
| Molecular Weight: | 14,954 Da |
| NCBI Full Name: | cell cycle exit and neuronal differentiation protein 1 |
| NCBI Synonym Full Names: | cell cycle exit and neuronal differentiation 1 |
| NCBI Official Symbol: | CEND1 |
| NCBI Official Synonym Symbols: | BM88 |
| NCBI Protein Information: | cell cycle exit and neuronal differentiation protein 1 |
| UniProt Protein Name: | Cell cycle exit and neuronal differentiation protein 1 |
| UniProt Synonym Protein Names: | BM88 antigen |
| UniProt Gene Name: | CEND1 |
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