Human CEACAM21 Recombinant Protein (RPPB3139)

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SKU:
RPPB3139
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
CEACAM21
Synonyms:
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 21
Synonyms:
CEACAM3
Synonyms:
R29124_1
Source:
Escherichia Coli
Uniprot:
Q3KPI0
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Description

Product Name:Human CEACAM21 Recombinant Protein
Product Code:RPPB3139
Size:20µg
Species:Human
Target:CEACAM21
Synonyms:Carcinoembryonic Antigen-Related Cell Adhesion Molecule 21, CEACAM3, R29124_1.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The CEACAM21 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSWLFIASA PFEVAEGENV HLSVVYLPEN LYSYGWYKGK TVEPNQLIAA YVIDTHVRTP GPAYSGRETI SPSGDLHFQN VTLEDTGYYN LQVTYRNSQI EQASHHLRVY ESVAQPSIQA SSTTVTEKGS VVLTCHTNNT GTSFQWIFNN QRLQVTKRMK LSWFNHVLTI DPIRQEDAGE YQCEVSNPVS SNRSDPLKLT VKSDDNTLG

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 21 (CEACAM21) belongs to the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by a number of bacterial pathogens to bind and invade host cells. The transmembrane protein guides phagocytosis of several bacterial species which is dependent on the small GTPase Rac. CEACAM21 is assumed to have a central role in controlling human-specific pathogens by the innate immune system. 

CEACAM21 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (35-240) and having a molecular mass of 25.0kDa.CEACAM21 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:CEACAM21: Belongs to the immunoglobulin superfamily. CEA family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Immunoglobulin superfamily; Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.2Cellular Component: integral to membrane
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q3KPI0
NCBI GenInfo Identifier:15080526
NCBI Gene ID:90273
NCBI Accession:BC012001
UniProt Secondary Accession:Q3KPI0,O75296, Q6UY47, Q96ER7, B7WNQ6
UniProt Related Accession:Q3KPI0
Molecular Weight:21,511 Da
NCBI Full Name:Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 21, mRNA
NCBI Synonym Full Names:carcinoembryonic antigen related cell adhesion molecule 21
NCBI Official Symbol:CEACAM21  
NCBI Official Synonym Symbols:CEACAM3; R29124_1  
NCBI Protein Information:carcinoembryonic antigen-related cell adhesion molecule 21
UniProt Protein Name:Carcinoembryonic antigen-related cell adhesion molecule 21
UniProt Synonym Protein Names:
Protein Family:Carcinoembryonic antigen-related cell adhesion molecule
UniProt Gene Name:CEACAM21  
UniProt Entry Name:CEA21_HUMAN
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