Human CEACAM21 Recombinant Protein (RPPB3139)
- SKU:
- RPPB3139
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- CEACAM21
- Synonyms:
- Carcinoembryonic Antigen-Related Cell Adhesion Molecule 21
- CEACAM3
- R29124_1
- Source:
- Escherichia Coli
- Uniprot:
- Q3KPI0
Description
| Product Name: | Human CEACAM21 Recombinant Protein |
| Product Code: | RPPB3139 |
| Size: | 20µg |
| Species: | Human |
| Target: | CEACAM21 |
| Synonyms: | Carcinoembryonic Antigen-Related Cell Adhesion Molecule 21, CEACAM3, R29124_1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The CEACAM21 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSWLFIASA PFEVAEGENV HLSVVYLPEN LYSYGWYKGK TVEPNQLIAA YVIDTHVRTP GPAYSGRETI SPSGDLHFQN VTLEDTGYYN LQVTYRNSQI EQASHHLRVY ESVAQPSIQA SSTTVTEKGS VVLTCHTNNT GTSFQWIFNN QRLQVTKRMK LSWFNHVLTI DPIRQEDAGE YQCEVSNPVS SNRSDPLKLT VKSDDNTLG |
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 21 (CEACAM21) belongs to the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by a number of bacterial pathogens to bind and invade host cells. The transmembrane protein guides phagocytosis of several bacterial species which is dependent on the small GTPase Rac. CEACAM21 is assumed to have a central role in controlling human-specific pathogens by the innate immune system.
CEACAM21 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (35-240) and having a molecular mass of 25.0kDa.CEACAM21 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CEACAM21: Belongs to the immunoglobulin superfamily. CEA family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Immunoglobulin superfamily; Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.2Cellular Component: integral to membrane |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q3KPI0 |
| NCBI GenInfo Identifier: | 15080526 |
| NCBI Gene ID: | 90273 |
| NCBI Accession: | BC012001 |
| UniProt Secondary Accession: | Q3KPI0,O75296, Q6UY47, Q96ER7, B7WNQ6 |
| UniProt Related Accession: | Q3KPI0 |
| Molecular Weight: | 21,511 Da |
| NCBI Full Name: | Homo sapiens carcinoembryonic antigen-related cell adhesion molecule 21, mRNA |
| NCBI Synonym Full Names: | carcinoembryonic antigen related cell adhesion molecule 21 |
| NCBI Official Symbol: | CEACAM21 |
| NCBI Official Synonym Symbols: | CEACAM3; R29124_1 |
| NCBI Protein Information: | carcinoembryonic antigen-related cell adhesion molecule 21 |
| UniProt Protein Name: | Carcinoembryonic antigen-related cell adhesion molecule 21 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Carcinoembryonic antigen-related cell adhesion molecule |
| UniProt Gene Name: | CEACAM21 |
| UniProt Entry Name: | CEA21_HUMAN |
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