The Human CD90 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated) (5E10) (AGEL1834) is a cutting-edge tool for researchers in the field of immunology and cell biology. This monoclonal antibody specifically targets CD90, a cell surface marker widely used for identifying and isolating various cell populations, including stem cells, fibroblasts, and immune cells.Designed for precise detection and analysis, this antibody offers high reactivity with human samples, ensuring reliable results in flow cytometry and immunofluorescence applications. The conjugation of PerCP-Cyanine5.5 enhances the detection sensitivity, enabling accurate visualization and quantification of CD90 expression in complex biological samples.CD90, also known as Thy-1 antigen, plays crucial roles in cell adhesion, migration, and signaling pathways, making it a valuable target for investigating cell behavior and function.
Research involving CD90 is instrumental in understanding processes such as tissue regeneration, inflammation, and cancer progression, offering insights into potential therapeutic strategies.With its exceptional specificity and sensitivity, the Human CD90 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated) (5E10) (AGEL1834) is a versatile tool for scientists exploring diverse areas of cell biology and immunology. Whether studying stem cell populations, characterizing fibroblast phenotypes, or investigating immune cell subsets, this antibody provides a reliable solution for precise detection and analysis, facilitating groundbreaking discoveries in research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04216
Gene ID:
7070
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90 is a 25-35 kD GPI-anchored protein, also known as Thy-1. It belongs to the Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+ cells, a subset of fetal liver cells and fetal thymocytes, fibroblasts, activated endothelial cells, and some leukemia cell lines. CD34+CD90+ cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with β2 and β3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, and inhibits hematopoietic stem cells proliferation and differentiation.