Human CD9 Recombinant Protein (RPPB3031)
- SKU:
- RPPB3031
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- CD9
- Synonyms:
- CD9 antigen
- 5H9 antigen
- Cell growth-inhibiting gene 2 protein
- Leukocyte antigen MIC3
- Source:
- Escherichia Coli
- Uniprot:
- P21926
Description
| Product Name: | Human CD9 Recombinant Protein |
| Product Code: | RPPB3031 |
| Size: | 20µg |
| Species: | Human |
| Target: | CD9 |
| Synonyms: | CD9 antigen, 5H9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, Motility-related protein, CD9, MRP-1, Tetraspanin-29, Tspan-29, p24, MIC3, TSPAN29, GIG2, BTCC-1, DRAP-27, TSPAN-29. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CD9 solution (0.25mg/1ml) contains Phosphate buffer saline (pH 7.4), 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSSHKDEVI KEVQEFYKDT YNKLKTKDEP QRETLKAIHY ALNCCGLAGG VEQFISDICP KKDVLETFTV KSCPDAIKEV FDNKFHI |
CD9 which is found on the surface of exosomes is a cell surface glycoprotein which is interacts with integrins and various transmembrane superfamily proteins. CD9 is involved in platelet activation and aggregation and also regulates paranodal junction formation. CD9 takes part in cell adhesion and migration and also promotes muscle cell fusion. CD9 is necessary for the egg-sperm fusion during mammalian fertilization.
CD9 Human Recombinant produced in E. coli is a single polypeptide chain containing 107 amino acids (112-195) and having a molecular mass of 12kDa.CD9 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CD9: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Belongs to the tetraspanin (TM4SF) family. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 12p13.31 Cellular Component: extracellular space; focal adhesion; integral to plasma membrane; membrane; plasma membrane; platelet alpha granule membrane Molecular Function:protein binding Biological Process: cell adhesion; cell motility; cell surface receptor linked signal transduction; fusion of sperm to egg plasma membrane; paranodal junction assembly; platelet degranulation; receptor internalization |
| NCBI Summary: | This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011] |
| UniProt Code: | P21926 |
| NCBI GenInfo Identifier: | 231724 |
| NCBI Gene ID: | 928 |
| NCBI Accession: | P21926.4 |
| UniProt Secondary Accession: | P21926,Q5J7W6, Q96ES4, D3DUQ9, |
| UniProt Related Accession: | P21926 |
| Molecular Weight: | |
| NCBI Full Name: | CD9 antigen |
| NCBI Synonym Full Names: | CD9 molecule |
| NCBI Official Symbol: | CD9 |
| NCBI Official Synonym Symbols: | MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29 |
| NCBI Protein Information: | CD9 antigen |
| UniProt Protein Name: | CD9 antigen |
| UniProt Synonym Protein Names: | 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD_antigen: CD9 |
| Protein Family: | CD9 antigen |
| UniProt Gene Name: | CD9 |
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