GenieFluor 488 Anti-Human CD8a Antibody [OKT-8] (AGEL0412)

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SKU:
AGEL0412
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
OKT-8
Conjugation:
AF 488
Applications:
FC
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD8a Antibody [OKT-8]

The Human CD8a Monoclonal Antibody (Alexa Fluor 488 Conjugated, OKT-8) is a cutting-edge tool for research in immunology and cell biology. This antibody, available from Assay Genie, specifically targets the CD8a protein, a key cell surface marker involved in immune responses and T cell function.The OKT-8 antibody is highly specific for human CD8a, enabling precise and reliable detection in various experimental settings. By conjugating Alexa Fluor 488 to the antibody, this product offers researchers the advantage of fluorescent visualization, allowing for the tracking and analysis of CD8a-expressing cells with high sensitivity and resolution.

Ideal for applications such as flow cytometry, immunofluorescence, and immunohistochemistry, the Human CD8a Monoclonal Antibody (Alexa Fluor 488 Conjugated, OKT-8) from Assay Genie is a valuable tool for investigating immune cell populations, understanding T cell dynamics, and exploring the role of CD8a in health and disease. Upgrade your research capabilities with this innovative antibody and gain deeper insights into the intricate mechanisms of the human immune system.

Product Title:GenieFluor 488 Anti-Human CD8a Antibody [OKT-8]
SKU:AGEL0412
Size:20 Tests, 100 Tests, 200 Tests
Clone No:OKT-8
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 488 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01732
Gene ID:925
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

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