PE/Cyanine5 Anti-Human CD86 Antibody [BU63] (AGEL0647)

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SKU:
AGEL0647
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody (PE/Cyanine5 Conjugated) (BU63) is a cutting-edge tool for researchers delving into immune responses and cellular interactions. This antibody, meticulously crafted for specificity and sensitivity, targets the CD86 protein - a key player in the activation of T cells and the modulation of immune responses.CD86, also known as B7-2, is a critical co-stimulatory molecule expressed on antigen-presenting cells that interacts with CD28 on T cells to provide the second signal necessary for T cell activation. By targeting CD86 with this high-quality antibody, researchers can investigate the dynamics of co-stimulatory signaling pathways and their implications in immune function.With its PE/Cyanine5 conjugation, this antibody offers the dual benefits of fluorescence detection and flow cytometry compatibility, allowing for precise and quantitative analysis of CD86 expression in various cell types.

Its versatility and reliability make it an invaluable tool for studies in immunology, transplantation, autoimmunity, and infectious diseases.Unlock the potential of your research with the Human CD86 Monoclonal Antibody (PE/Cyanine5 Conjugated) (BU63) - a sophisticated reagent designed to enhance understanding of immune regulation and T cell activation mechanisms. Trust in its performance to illuminate the complexities of immune responses and pave the way for innovative discoveries in biomedical science.

Product Title:PE/Cyanine5 Anti-Human CD86 Antibody [BU63]
SKU:AGEL0647
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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