PE/Cyanine5.5 Anti-Human CD86 Antibody [BU63] (AGEL0649)

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SKU:
AGEL0649
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody PE-Cyanine5.5 Conjugated (BU63) is a cutting-edge tool designed for precise and efficient detection of the CD86 protein in human samples. CD86, also known as B7-2, is a crucial co-stimulatory molecule involved in immune responses, making it a key target for research in immunology and related fields.This monoclonal antibody, conjugated with PE-Cyanine5.5 for enhanced detection sensitivity, offers high specificity and sensitivity in a variety of applications. Whether utilized in flow cytometry, immunofluorescence, or other techniques, this antibody provides reliable and reproducible results for studying CD86 expression in different cell types and experimental conditions.

By targeting CD86, researchers can gain valuable insights into immune activation, T-cell co-stimulation, and the regulation of immune responses. This antibody is a valuable tool for investigating immune-related diseases, understanding immune cell interactions, and developing targeted immunotherapies.Overall, the Human CD86 Monoclonal Antibody PE-Cyanine5.5 Conjugated (BU63) from AssayGenie is an essential resource for researchers aiming to deepen their understanding of immune system dynamics and explore the role of CD86 in health and disease.

Product Title:PE/Cyanine5.5 Anti-Human CD86 Antibody [BU63]
SKU:AGEL0649
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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