The Human CD69 Monoclonal Antibody - PercP-Cyanine5.5 Conjugated (FN50) is a powerful tool for researchers studying CD69, a key cell surface marker involved in immune activation and regulation. This monoclonal antibody, conjugated to PercP-Cyanine5.5, offers high specificity and sensitivity for detecting CD69 in human samples, making it an essential reagent for flow cytometry and cell signaling studies.CD69, also known as the very early activation antigen, is rapidly induced upon immune cell activation, serving as a marker for early stages of immune response. Its expression is linked to T cell activation, cytokine production, and lymphocyte proliferation, making it a crucial player in adaptive immunity and inflammatory processes. Studying CD69 dynamics can provide valuable insights into immune cell function, response to pathogens, and development of immunotherapies for various diseases.
With its validated performance in flow cytometry and immunophenotyping, this CD69 monoclonal antibody facilitates precise identification and characterization of CD69-expressing cell populations in diverse experimental settings. Whether investigating immune cell activation, differentiation, or response to therapeutic interventions, this antibody is a reliable tool for unraveling the intricate mechanisms of immune regulation and host defense.Enhance your research capabilities and delve deeper into the complexities of immune activation with the Human CD69 Monoclonal Antibody - PercP-Cyanine5.5 Conjugated (FN50). Unlock new insights into immune cell dynamics, disease mechanisms, and therapeutic targets with this cutting-edge antibody reagent.
Product Title:
PerCP/Cyanine5.5 Anti-Human CD69 Antibody [FN50]
SKU:
AGEL1693
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
FN50
Synonyms:
Early activation antigen CD69;Activation inducer molecule;AIM;EA1;MLR-3;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q07108
Gene ID:
969
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.