The Human CD64 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (AGEL1119) offered by AssayGenie is a cutting-edge tool for researchers studying the CD64 protein, a key receptor involved in immune responses. This monoclonal antibody, conjugated with PerCP-Cyanine5.5, specifically targets human CD64 and is optimized for flow cytometry applications. Its high specificity and sensitivity make it ideal for detecting and quantifying CD64 expression in various cell types, providing valuable insights into immune system function and inflammatory processes.
CD64, also known as Fc-gamma receptor I, plays a crucial role in the activation of immune cells and the uptake of antibodies. Its dysregulation has been implicated in a range of diseases, including autoimmune disorders, infectious diseases, and cancer. By utilizing the Human CD64 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (AGEL1119), researchers can delve deeper into the mechanisms involving CD64, paving the way for the development of targeted therapies and diagnostic tools for various conditions where CD64 dysregulation is a factor.
Product Title:
PerCP/Cyanine5.5 Anti-Human CD64 Antibody [10.1]
SKU:
AGEL1119
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
10.1
Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P12314
Gene ID:
2209
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).