The Human CD64 Monoclonal Antibody (PE/Cyanine7 conjugated) is a cutting-edge tool for researchers investigating the CD64 protein, a key component of the human immune system. This antibody, meticulously crafted for specificity and sensitivity, offers a powerful method for detecting and analyzing CD64 expression in various cell types. By binding with high affinity to the CD64 protein, this antibody facilitates precise detection and quantification, making it a valuable asset in immunology and cancer research studies.CD64, also known as Fc-gamma receptor I, plays a crucial role in immune response modulation by mediating the recognition and clearance of pathogens and immune complexes. Its involvement in antibody-dependent cellular cytotoxicity and phagocytosis underscores its significance in both innate and adaptive immunity.
Research into CD64's function is vital for unraveling its impact on immune signaling pathways, infection responses, and inflammatory processes, with potential implications for therapeutic interventions in conditions such as infectious diseases and immune disorders.The Human CD64 Monoclonal Antibody (PE/Cyanine7 conjugated) epitomizes precision and reliability in immunological research, providing researchers with a specialized tool for unraveling the complexities of immune regulation and response pathways. Explore the intricacies of CD64 biology with confidence and clarity using this state-of-the-art antibody, opening new avenues for understanding immune function and developing targeted therapies in the field of biomedicine.
Product Title:
PE/Cyanine7 Anti-Human CD64 Antibody [10.1]
SKU:
AGEL1117
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
10.1
Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P12314
Gene ID:
2209
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).