The Human CD64 Monoclonal Antibody (APC Conjugated) (AGEL0315) from Assay Genie is a cutting-edge tool for researchers investigating CD64, a pivotal cell surface receptor involved in immune responses. This monoclonal antibody, specifically designed for human samples, is conjugated with APC (Allophycocyanin) for enhanced detection capabilities.CD64, also known as Fc-gamma receptor I, plays a crucial role in mediating immune functions by binding to the Fc portion of immunoglobulin G (IgG) antibodies. Its expression on various immune cell types makes it a key player in both innate and adaptive immune responses. The Human CD64 Monoclonal Antibody enables precise detection and quantitative analysis of CD64 protein levels in different cell types, offering valuable insights into immune system dynamics.
This powerful antibody is essential for studies in immunology, infectious diseases, and antibody-mediated immune responses. Its superior specificity and sensitivity make it ideal for applications such as flow cytometry, immunofluorescence, and immunohistochemistry, providing researchers with a comprehensive toolkit for exploring the functions of CD64 in health and disease.By leveraging the Human CD64 Monoclonal Antibody (APC Conjugated) from Assay Genie, researchers can delve deeper into the intricate mechanisms of immune regulation and inflammatory pathways, paving the way for innovative therapeutic strategies and advances in precision medicine.
Product Title:
APC Anti-Human CD64 Antibody [10.1]
SKU:
AGEL0315
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
10.1
Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P12314
Gene ID:
2209
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).