The Human CD64 Monoclonal Antibody (Alexa Fluor 488 conjugated) (AGEL0316) from AssayGenie is a cutting-edge tool for researchers studying CD64, a vital cell surface receptor involved in immune responses. This monoclonal antibody, conjugated with Alexa Fluor 488 for fluorescent detection, has been meticulously designed to offer high specificity and sensitivity in detecting CD64 expression in human samples.CD64, also known as Fc-gamma receptor I, plays a key role in mediating immune responses, particularly in phagocytosis and antigen presentation. The Human CD64 Monoclonal Antibody is optimized for various applications, including flow cytometry and immunofluorescence, enabling precise visualization and quantification of CD64-expressing cells in biological samples.
With its advanced conjugation technology and specificity for CD64, this antibody is a valuable asset for researchers investigating immune functions, infectious diseases, and inflammatory conditions. Its reliable performance and compatibility with multiple experimental techniques make it an indispensable tool for enhancing our understanding of immune system dynamics and developing targeted therapies in immunology and infectious disease research.
Product Title:
GenieFluor 488 Anti-Human CD64 Antibody [10.1]
SKU:
AGEL0316
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
10.1
Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P12314
Gene ID:
2209
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).