The Human CD64 Monoclonal Antibody (AF647 Conjugated) is a cutting-edge tool for researchers studying CD64, a key cell surface receptor involved in immune responses. This antibody, conjugated with AF647 for enhanced detection, is specifically designed for use in flow cytometry and immunofluorescence applications. It binds specifically to the CD64 protein, enabling precise detection and analysis in human samples across various cell types.CD64, also known as Fc-gamma receptor 1, plays a crucial role in immune defense by mediating the uptake of antibodies and promoting immune signaling.
Understanding the function and expression of CD64 is essential for unraveling immune activation pathways in conditions such as infections, autoimmune diseases, and inflammatory disorders. The Human CD64 Monoclonal Antibody (AF647 Conjugated) is a valuable resource for researchers aiming to elucidate the role of CD64 in immunology, paving the way for potential therapeutic interventions targeting this receptor.
Product Title:
GenieFluor 647 Anti-Human CD64 Antibody [10.1]
SKU:
AGEL1120
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
10.1
Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P12314
Gene ID:
2209
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
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