Purified Anti-Human CD64 Antibody [10.1] (AGEL0312)

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SKU:
AGEL0312
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
10.1
Conjugation:
Unconjugated
Applications:
FC
IHC
Frequently bought together:

Description

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Purified Anti-Human CD64 Antibody [10.1]

The Human CD64 Monoclonal Antibody (10-1) is a cutting-edge tool designed for researchers studying CD64, a crucial cell surface receptor known for its role in immune responses and inflammation. This monoclonal antibody, meticulously crafted and validated by AssayGenie, boasts high specificity and reactivity towards human samples, ensuring accurate and reliable results in a variety of experimental settings.CD64, also referred to as FcγRI, serves as a key component in the immune system, particularly in mediating responses triggered by antibodies. Its diverse functions span from enhancing phagocytosis to modulating cytokine production, making it a fascinating target for investigations spanning immunology, infectious diseases, and autoimmune disorders.

By utilizing the CD64 Monoclonal Antibody (10-1), researchers can gain deeper insights into the intricate mechanisms involving this receptor and its implications in various physiological and pathological conditions.With its exceptional performance in techniques such as Western blotting and immunohistochemistry, this antibody empowers researchers to detect and analyze CD64 expression in different cell types and tissues with precision. By unraveling the intricate roles of CD64 in immune regulation and disease pathogenesis, this monoclonal antibody paves the way for cutting-edge discoveries and advancements in the fields of immunology and therapeutic development.

Product Title:Purified Anti-Human CD64 Antibody [10.1]
SKU:AGEL0312
Size:25µg, 100µg
Clone No:10.1
Synonyms:Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P12314
Gene ID:2209
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

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