FITC Anti-Human CD61 Antibody [VI-PL2] (AGEL1825)

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SKU:
AGEL1825
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Human CD61 Antibody [VI-PL2]

The Human CD61 Monoclonal Antibody FITC Conjugated (VI-PL2-AGEL1825) from AssayGenie is a specialized tool for targeted research involving the CD61 antigen. CD61, also known as integrin beta 3, is a cell surface glycoprotein that plays a key role in platelet aggregation and adhesion, making it crucial for various physiological processes such as hemostasis and wound healing.This monoclonal antibody, conjugated with FITC for fluorescent detection, is highly specific and sensitive for human samples, making it an ideal choice for immunofluorescence and flow cytometry applications. By binding to the CD61 antigen, researchers can visualize and quantify the expression of this important protein in different cell types and tissues, providing valuable insights into platelet function, thrombosis, and related disorders.

With its reliable performance and validation for specific applications, the Human CD61 Monoclonal Antibody FITC Conjugated offers a valuable tool for studies in hematology, vascular biology, and clinical diagnostics. Researchers can leverage this antibody to further understand the role of CD61 in health and disease, paving the way for advancements in therapeutic interventions targeting platelet function and vascular disorders.

Product Title:FITC Anti-Human CD61 Antibody [VI-PL2]
SKU:AGEL1825
Size:20 Tests, 100 Tests, 200 Tests
Clone No:VI-PL2
Synonyms:GP3A;GPIIIa;ITGB3;Integrin beta-3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05106
Gene ID:3690
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.

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