Human CD5L Recombinant Protein (RPPB3022)

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SKU:
RPPB3022
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
CD5L
Synonyms:
CD5 antigen-like
Synonyms:
CT-2
Synonyms:
IgM-associated peptide
Synonyms:
SP-alpha
Source:
Escherichia Coli
Uniprot:
O43866
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Description

Product Name:Human CD5L Recombinant Protein
Product Code:RPPB3022
Size:10µg
Species:Human
Target:CD5L
Synonyms:CD5 antigen-like, CT-2, IgM-associated peptide, SP-alpha, CD5L, API6, AIM, API6, PRO229, Spalpha.
Source:Escherichia Coli
Physical Appearance:Filtered White lyophilized (freeze-dried) powder.
Formulation:CD5L filtered (0.4 µm) and lyophilized from 0.5mg/ml in 50mM Tris buffer, pH 8.6.
Solubility:It is recommended to add 200µl deionized water to a working concentration of 0.5mg/ml and let the lyophilized pellet dissolve completely. CD5L is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Stability:Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MKHHHHHHAS PSGVRLVGGL HRCEGRVEVE QKGQWGTVCD DGWDIKDVAV LCRELGCGAA SGTPSGILYE PPAEKEQKVL IQSVSCTGTE DTLAQCEQEE VYDCSHDEDA GASCENPESS FSPVPEGVRL ADGPGHCKGR VEVKHQNQWY TVCQTGWSLR AAKVVCRQLG CGRAVLTQKR CNKHAYGRKP IWLSQMSCSG REATLQDCPS GPWGKNTCNH DEDTWVECED PFDLRLVGGD NLCSGRLEVL HKGVWGSVCD DNWGEKEDQV VCKQLGCGKS LSPSFRDRKC YGPGVGRIWL DNVRCSGEEQ SLEQCQHRFW GFHDCTHQED VAVICSG

CD5 antigen-like (CD5L) participates in the regulation of the immune system. CD5L functions as an inhibitor of apoptosis. CD5L is expressed in the spleen, lymph node, thymus and bone marrow.

CD5L Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 20-347) containing 337 amino acids including a 9 a.a N-terminal His tag. The total molecular mass is 37.2kDa (calculated).

UniProt Protein Function:CD5L: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis.
UniProt Protein Details:

Protein type:Receptor, misc.; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function:scavenger receptor activity

Biological Process: receptor-mediated endocytosis; apoptosis; cellular defense response

UniProt Code:O43866
NCBI GenInfo Identifier:20177834
NCBI Gene ID:922
NCBI Accession:O43866.1
UniProt Secondary Accession:O43866,Q6UX63, A8K7M5,
UniProt Related Accession:O43866
Molecular Weight:347
NCBI Full Name:CD5 antigen-like
NCBI Synonym Full Names:CD5 molecule-like
NCBI Official Symbol:CD5L  
NCBI Official Synonym Symbols:AIM; API6; PRO229; Spalpha; SP-ALPHA  
NCBI Protein Information:CD5 antigen-like; CT-2; apoptosis inhibitor 6; igM-associated peptide; CD5 antigen-like (scavenger receptor cysteine rich family)
UniProt Protein Name:CD5 antigen-like
UniProt Synonym Protein Names:CT-2; IgM-associated peptide; SP-alpha
Protein Family:CD5 antigen
UniProt Gene Name:CD5L  
UniProt Entry Name:CD5L_HUMAN
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