Human CD58 Recombinant Protein (RPPB3082)
- SKU:
- RPPB3082
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- CD58
- Synonyms:
- ag3
- LFA-3
- LFA3
- CD58 molecule
- Source:
- Escherichia Coli
- Uniprot:
- P19256
Frequently bought together:
Description
Product Name: | Human CD58 Recombinant Protein |
Product Code: | RPPB3082 |
Size: | 20µg |
Species: | Human |
Target: | CD58 |
Synonyms: | ag3, LFA-3, LFA3, CD58 molecule, Lymphocytefunction-associated antigen 3, Ag3, Surfaceglycoprotein LFA-3. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile Filtered clear solution. |
Formulation: | CD58 protein solution (1mg/ml) containing 20mM Phosphatebuffer and 10% glycerol. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Purity: | Greater than 90.0% as determined by SDS-PAGE. |
Amino Acid Sequence: | MGSSHHHHHHSSGLVPRGSH MGSFSQQIYGVVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEMESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYFKMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR |
CD58 is part of the immunoglobulin superfamily. CD58 is a ligand of the T lymphocyte CD2 protein, and is invloved in adhesion and activation of T lymphocytes. CD58 is localized to the plasma membrane.
CD58 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (29-215 a.a) and having a molecular mass of 23.8kDa.CD58 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques
UniProt Protein Function: | Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. |
NCBI Summary: | This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] |
UniProt Code: | P19256 |
NCBI GenInfo Identifier: | 126225 |
NCBI Gene ID: | 965 |
NCBI Accession: | P19256.1 |
UniProt Secondary Accession: | P19256,Q5U053, Q6IB65, Q96KI9, A8K7G5, |
UniProt Related Accession: | P19256 |
Molecular Weight: | 27,960 Da |
NCBI Full Name: | Lymphocyte function-associated antigen 3 |
NCBI Synonym Full Names: | CD58 molecule |
NCBI Official Symbol: | CD58 |
NCBI Official Synonym Symbols: | ag3; LFA3; LFA-3 |
NCBI Protein Information: | lymphocyte function-associated antigen 3 |
UniProt Protein Name: | Lymphocyte function-associated antigen 3 |
UniProt Synonym Protein Names: | Surface glycoprotein LFA-3; CD_antigen: CD58 |
Protein Family: | Lymphocyte function-associated antigen |
UniProt Gene Name: | CD58 |