PE/Cyanine7 Anti-Human CD57 Antibody [HNK-1] (AGEL1034)

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SKU:
AGEL1034
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD57 Antibody [HNK-1]

The Human CD57 Monoclonal Antibody (PE/Cyanine7 Conjugated, HNK-1) - AGEL1034 from Assay Genie is a cutting-edge tool for research in immunology and cell biology. This monoclonal antibody is specially designed for the detection and analysis of CD57, a cell surface marker associated with natural killer cells and a subset of T cells.CD57, also known as HNK-1, is a marker of human lymphocytes with reduced proliferative capacity and increased cytotoxic potential. The conjugation of PE/Cyanine7 to this antibody allows for highly sensitive detection and quantification of CD57-expressing cells by flow cytometry and fluorescence microscopy.

This antibody is ideal for studying immune responses, cell-mediated cytotoxicity, and identifying specific lymphocyte subsets in research related to infectious diseases, cancer immunotherapy, and autoimmune disorders. With its high specificity and validated performance in various experimental techniques, the Human CD57 Monoclonal Antibody (PE/Cyanine7 Conjugated, HNK-1) - AGEL1034 is a valuable tool for advancing scientific understanding in immunology and related fields.

Product Title:PE/Cyanine7 Anti-Human CD57 Antibody [HNK-1]
SKU:AGEL1034
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HNK-1
Synonyms:HNK-1; NK-1; Leu-7;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgM, κ
Isotype Control:PE/Cyanine7 Mouse IgM, κ Isotype Control[MM-30]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:27087
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

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