PE/Cyanine5 Anti-Human CD57 Antibody [HNK-1] (AGEL1033)

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SKU:
AGEL1033
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD57 Antibody [HNK-1]

The Human CD57 Monoclonal Antibody PE/Cyanine5 Conjugated (HNK-1) is a powerful tool for investigating CD57, a marker associated with natural killer cells and subsets of T cells. This antibody, conjugated to both PE and Cyanine5, allows for multi-color flow cytometry analysis with high sensitivity and specificity. CD57, also known as HNK-1 or LEU-7, is involved in immune responses and has been linked to various diseases including viral infections and autoimmune disorders.

By targeting CD57, researchers can gain insights into the role of natural killer cells and T cell subsets in immunity and diseases.This antibody is ideal for immunophenotyping studies, cell sorting, and biomarker analysis in research areas such as immunology, oncology, and infectious diseases. Its conjugation to PE and Cyanine5 facilitates fluorescence-based detection, making it a valuable tool for investigating the role of CD57 in immune cell populations.

Product Title:PE/Cyanine5 Anti-Human CD57 Antibody [HNK-1]
SKU:AGEL1033
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HNK-1
Synonyms:HNK-1; NK-1; Leu-7;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgM, κ
Isotype Control:PE/Cyanine5 Mouse IgM, κ Isotype Control[MM-30]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:27087
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

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