Biotin Anti-Human CD57 Antibody [HNK-1] (AGEL0267)

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SKU:
AGEL0267
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgM
Clone:
HNK-1
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

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Biotin Anti-Human CD57 Antibody [HNK-1]

The Human CD57 Monoclonal Antibody (Biotin Conjugated) - HNK-1 (AGEL0267) is a specialized reagent designed for research involving CD57, a cell surface marker associated with natural killer cells and other immune cell subsets. This antibody, produced using monoclonal technology, exhibits high specificity and sensitivity for human CD57 samples, making it a valuable tool for immunology and oncology studies.CD57, also known as HNK-1 (human natural killer-1) antigen, serves as a marker for a subset of natural killer cells and other immune cell populations involved in immune responses and surveillance. By targeting CD57, researchers can analyze and identify these specific cell populations in various biological samples, enabling detailed investigations into immune function and cell-mediated immune responses.The biotin conjugation of this monoclonal antibody allows for versatile detection and analysis methods, including immunohistochemistry, flow cytometry, and other immunological assays.

Its application extends to studies exploring immune cell characteristics, biomarker expression in cancer research, and immune cell profiling in diseases such as autoimmune disorders and infectious diseases.Overall, the Human CD57 Monoclonal Antibody (Biotin Conjugated) - HNK-1 (AGEL0267) serves as a critical tool for researchers investigating immune cell subsets, natural killer cell activity, and immune responses in health and disease contexts. Its specificity and versatility make it an essential component for advancing our understanding of immune system functionality and its implications in various pathological conditions.

Product Title:Biotin Anti-Human CD57 Antibody [HNK-1]
SKU:AGEL0267
Size:25µg, 100µg
Clone No:HNK-1
Synonyms:HNK-1; NK-1; Leu-7;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgM, κ
Isotype Control:Biotin Mouse IgM, κ Isotype Control[MM-30]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Gene ID:27087
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

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