The Human CD57 Monoclonal Antibody (APC Conjugated) is a cutting-edge tool for researchers delving into the realm of immunology and cell biology. Specifically designed to target CD57, a marker associated with natural killer cells and some T cells, this antibody is a powerful ally in understanding immune responses and cellular interactions.With its APC conjugation, this monoclonal antibody offers high sensitivity and specificity in flow cytometry applications, allowing for precise identification and quantification of CD57-expressing cells. Whether investigating immune cell populations in cancer research, infectious diseases, or autoimmune disorders, this antibody provides valuable insights into the role of CD57 in immune function.
By enabling researchers to visualize and analyze CD57 expression in various cell types, this antibody opens up new avenues for exploring immune responses and disease pathogenesis. Its reliable performance and consistent results make it an indispensable tool for scientists seeking to unravel the complexities of the human immune system.Embark on your next research journey with the Human CD57 Monoclonal Antibody (APC Conjugated) and unlock the secrets of immune cell dynamics and function with precision and accuracy.
Product Title:
APC Anti-Human CD57 Antibody [HNK-1]
SKU:
AGEL0269
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
HNK-1
Synonyms:
HNK-1; NK-1; Leu-7;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgM, κ
Isotype Control:
APC Mouse IgM, κ Isotype Control[MM-30]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
27087
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).