The Human CD5 Monoclonal Antibody PE/Cyanine5 Conjugated (UCHT2) (AGEL0890) is a versatile tool designed for immunological research applications. This antibody specifically targets the CD5 protein, a cell surface marker predominantly expressed on T cells and involved in T cell receptor signaling and activation.With its PE/Cyanine5 conjugation, this antibody enables multi-color flow cytometry analysis, allowing for the simultaneous detection of CD5 along with other cell surface markers. The UCHT2 clone used in this antibody offers high specificity and sensitivity for human samples, making it a reliable choice for various experimental settings.The CD5 protein is known for its role in T cell development, activation, and tolerance.
Research involving CD5 can provide valuable insights into immune responses, autoimmune diseases, and T cell-mediated disorders. By targeting CD5 with this monoclonal antibody, researchers can explore the functions and dynamics of T cells more effectively, advancing our understanding of immune system regulation and diseases.Overall, the Human CD5 Monoclonal Antibody PE/Cyanine5 Conjugated (UCHT2) (AGEL0890) is a valuable tool for investigating T cell biology, immune responses, and potential therapeutic strategies targeting CD5-related pathways. Its specificity, conjugation, and compatibility with flow cytometry make it an essential component of immunology studies aimed at unraveling the complexities of the human immune system.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06127
Gene ID:
921
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.