The Human CD5 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) - UCHT2 (AGEL0892) is a specialized tool for researchers investigating CD5, a surface marker found on T cells and B-1a cells. This monoclonal antibody, conjugated with PE/Cyanine5.5, offers high specificity and sensitivity in detecting and analyzing CD5 expression in human samples, particularly in flow cytometry applications.CD5 is a key regulator of T and B cell signaling, playing a crucial role in immune responses and tolerance. Its expression profile and signaling pathways have been linked to various immune-related disorders, making it a promising target for immunotherapy research. By utilizing this antibody, researchers can explore the function and distribution of CD5 in different cell populations, shedding light on its role in autoimmune diseases, hematological malignancies, and immune responses.
The Human CD5 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) - UCHT2 (AGEL0892) provides a reliable tool for studying CD5 dynamics and interactions in the context of immune system modulation and disease pathology. Its optimized formulation and validation ensure consistent and reproducible results, making it a valuable asset for immunologists, oncologists, and researchers delving into the intricate mechanisms of immune regulation.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06127
Gene ID:
921
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.