The Human CD5 Monoclonal Antibody (Alexa Fluor 488 Conjugated) (UCHT2) (AGEL0191) offered by AssayGenie is a cutting-edge tool for researchers studying CD5, a vital cell surface marker involved in lymphocyte development and signal transduction. This monoclonal antibody, conjugated with Alexa Fluor 488, provides high specificity and sensitivity in detecting CD5 in human samples, making it ideal for flow cytometry and immunofluorescence applications.CD5 is a key player in immune responses, acting as a regulator of T-cell activation and survival. Its dysregulation has been linked to various immunological disorders and cancers, emphasizing the importance of studying its function.
With the AGEL0191 antibody, researchers can accurately visualize and quantify CD5 expression in different cell populations, aiding in the exploration of immune system dynamics and the development of targeted therapies.Utilizing this advanced antibody, scientists can delve deeper into the role of CD5 in immune cell function, paving the way for breakthroughs in immunotherapy, autoimmune disease research, and cancer immunology. Access this innovative tool from AssayGenie to advance your understanding of CD5 biology and drive progress in immunological investigations.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06127
Gene ID:
921
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.