The Human CD5 Monoclonal Antibody (AF647 Conjugated) (UCHT2) is a powerful tool for researchers studying CD5, a cell surface glycoprotein primarily found on T cells and B-1a cells. This monoclonal antibody, conjugated with AF647 fluorophore, offers high specificity and sensitivity for detecting CD5 in human samples, making it ideal for flow cytometry and immunofluorescence applications.CD5 is a key regulator of immune responses, involved in signal transduction and lymphocyte activation. Its expression pattern and function in immune cells make it a vital target for investigating various diseases, including autoimmune disorders and lymphoid malignancies.
By precisely binding to CD5, this monoclonal antibody facilitates the identification and analysis of CD5-expressing cells, providing valuable insights into immune cell behavior and function.Researchers focused on immunology, cancer biology, and autoimmune diseases will find this CD5 Monoclonal Antibody invaluable for exploring the role of CD5 in immune system modulation and disease pathogenesis. With its proven reliability and specificity, this antibody is a valuable asset for advancing research in these important areas of biomedicine.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06127
Gene ID:
921
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.