Human CD48 Recombinant Protein (RPPB3077)
- SKU:
- RPPB3077
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- CD48
- Synonyms:
- CD48 antigen
- B-lymphocyte activation marker BLAST-1
- BCM1 surface antigen
- Leukocyte antigen MEM-102
- Source:
- Sf9 Insect cells
- Uniprot:
- P09326
Description
| Product Name: | Human CD48 Recombinant Protein |
| Product Code: | RPPB3077 |
| Size: | 10µg |
| Species: | Human |
| Target: | CD48 |
| Synonyms: | CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, SLAM family member 2, SLAMF2, Signaling lymphocytic activation molecule 2, TCT.1. |
| Source: | Sf9 Insect cells |
| Formulation: | NECTIN2 protein solution (1.0mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPQGHLVHM TVVSGSNVTL NISESLPENY KQLTWFYTFD QKIVEWDSRK SKYFESKFKG RVRLDPQSGA LYISKVQKED NSTYIMRVLK KTGNEQEWKI KLQVLDPVPK PVIKIEKIED MDDNCYLKLS CVIPGESVNY TWYGDKRPFP KELQNSVLET TLMPHNYSRC YTCQVSNSVSSKNGTVCLSP PCTLARSHHH HHH |
CD48, is a GPI-linked protein which belongs to the CD2 family of immunoglobulin superfamily molecules. CD48 is capable to transduce signals and can likewise trigger signaling through CD2 or 2B4. CD48 to CD2 interactions advocate T cell activation and class replacing to IgG2a in B cells. In addition, high affinity of CD48 to 2B4, interactions may either promote or inhibit NK cell as well as cytotoxic T cell (CTL) activation. CD48 does not contain a transmembrane domain, though it is held at the cell surface by a GPI anchor through a C-terminal domain which possibly split to produce a soluble form of the receptor.
CD48 Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 203 amino acids (27-220a.a.) and having a molecular mass of 23.4kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).CD48 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. |
| UniProt Code: | P09326 |
| NCBI GenInfo Identifier: | |
| NCBI Gene ID: | |
| NCBI Accession: | P09326.2 |
| Molecular Weight: | 28kDa |
| NCBI Full Name: | |
| UniProt Protein Name: | CD48 antigen |
| UniProt Synonym Protein Names: | B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD_antigen: CD48 |
| Protein Family: | CD48 antigen |
| UniProt Gene Name: | CD48 |
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