FITC Anti-Human CD45RO Antibody [UCHL1] (AGEL1696)

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SKU:
AGEL1696
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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FITC Anti-Human CD45RO Antibody [UCHL1]

The Human CD45RO Monoclonal Antibody (FITC Conjugated) UCHL1 (AGEL1696) is a powerful tool for researchers studying immune responses and cell types expressing CD45RO. This antibody, conjugated with FITC for fluorescence detection, specifically targets the UCHL1 antigen, allowing for precise detection and analysis in various biological samples.CD45RO is a cellular marker associated with memory T cells in the immune system, playing a vital role in adaptive immune responses. By targeting CD45RO with this monoclonal antibody, researchers can delve into the mechanisms underlying immune memory and cellular responses in health and disease. The fluorescence conjugation of FITC enhances the visualization and localization of CD45RO-expressing cells, providing valuable insights into immune cell populations and their functions.

This monoclonal antibody is meticulously validated for its specificity and sensitivity in immunofluorescence applications, making it an indispensable tool for immunologists, cancer researchers, and investigators studying immune-related disorders. With its ability to precisely target CD45RO and enable robust detection, the Human CD45RO Monoclonal Antibody (FITC Conjugated) UCHL1 (AGEL1696) is poised to advance research efforts aimed at understanding immune responses and immune cell subsets in various biological contexts.

Product Title:FITC Anti-Human CD45RO Antibody [UCHL1]
SKU:AGEL1696
Size:20 Tests, 100 Tests, 200 Tests
Clone No:UCHL1
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

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