APC Anti-Human CD45RO Antibody [UCHL1] (AGEL1698)

(No reviews yet) Write a Review
SKU:
AGEL1698
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

APC Anti-Human CD45RO Antibody [UCHL1]

The Human CD45RO Monoclonal Antibody (APC-conjugated) UCHL1 (AGEL1698) offered by Assay Genie is a cutting-edge tool for researchers delving into the intricacies of the immune system. This antibody, derived from the UCHL1 clone, specifically targets the CD45RO protein, a marker present on memory T cells. By utilizing this antibody in flow cytometry, immunofluorescence, and other assay techniques, researchers can gain valuable insights into the function and behavior of memory T cells in immune responses.CD45RO is a critical player in adaptive immunity, serving as a memory marker that distinguishes antigen-experienced T cells. Understanding the dynamics of memory T cells is essential for unraveling immune responses to pathogens, vaccines, and various diseases.

The APC-conjugated UCHL1 antibody provides a precise tool for identifying and studying CD45RO-expressing cells, facilitating detailed investigations into memory T cell populations in diverse research settings.Whether exploring T cell memory formation, immune memory in disease pathogenesis, or vaccine efficacy assessments, the Human CD45RO Monoclonal Antibody (APC-conjugated) UCHL1 (AGEL1698) from Assay Genie is a valuable asset for researchers seeking to deepen their understanding of immune responses and memory T cell biology.

Product Title:APC Anti-Human CD45RO Antibody [UCHL1]
SKU:AGEL1698
Size:20 Tests, 100 Tests, 200 Tests
Clone No:UCHL1
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

0 Reviews

View AllClose

Related Products