GenieFluor 647 Anti-Human CD45RO Antibody [UCHL1] (AGEL1705)

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SKU:
AGEL1705
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD45RO Antibody [UCHL1]

The Human CD45RO Monoclonal Antibody (AF647 Conjugated) (UCHL1), catalog number AGEL1705, offered by AssayGenie, is a cutting-edge tool designed for advanced research applications in immunology and cell biology. This highly specific antibody targets CD45RO, a cell surface marker predominantly expressed on memory T cells and a subset of B cells.Derived from the UCHL1 clone, this monoclonal antibody is conjugated with AF647 for convenient fluorescent detection, making it ideal for flow cytometry and immunofluorescence assays. With a high level of sensitivity and specificity, researchers can confidently analyze and quantify CD45RO expression in various cell populations, providing valuable insights into immune responses and cell differentiation processes.By utilizing the Human CD45RO Monoclonal Antibody (AF647 Conjugated) (UCHL1), investigators can delve deeper into the dynamic interplay of immune cells within the body, unraveling mechanisms underlying immunity, infection, and disease progression.

Whether investigating T cell memory formation, immune cell activation, or disease biomarkers, this antibody serves as a versatile tool for elucidating complex biological processes at the cellular level.Enhance your research capabilities and unlock new discoveries with the Human CD45RO Monoclonal Antibody (AF647 Conjugated) (UCHL1) from AssayGenie. Discover the intricate world of immune cell dynamics and pave the way for pioneering advancements in immunotherapy, infectious disease research, and personalized medicine.

Product Title:GenieFluor 647 Anti-Human CD45RO Antibody [UCHL1]
SKU:AGEL1705
Size:20 Tests, 100 Tests, 200 Tests
Clone No:UCHL1
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 647 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

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