PE/Cyanine7 Anti-Human CD45RA Antibody [HI100] (AGEL0958)

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SKU:
AGEL0958
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD45RA Antibody [HI100]

The Human CD45RA Monoclonal Antibody (PE/Cyanine7 Conjugated, HI100, AGEL0958) offered by Assay Genie is a cutting-edge tool for researchers delving into the realm of immune cell characterization. This antibody, derived from hybridoma cells, exhibits a high level of specificity and sensitivity towards the CD45RA antigen, a marker associated with naive T cells and memory T cells.With its PE/Cyanine7 fluorophore conjugation, this antibody allows for precise and reliable detection of CD45RA expression in human samples through flow cytometry analysis. Its unparalleled performance in fluorescence-based assays makes it a standout choice for investigating T cell subsets and immune cell activation states in both normal and diseased conditions.

By targeting CD45RA, researchers can gain valuable insights into the dynamic immune responses underlying various diseases, including autoimmune disorders, infectious diseases, and cancer. The ability to identify and characterize specific T cell populations using this antibody opens doors to uncovering novel therapeutic targets and developing tailored immunotherapy strategies.In summary, the Human CD45RA Monoclonal Antibody (PE/Cyanine7 Conjugated) from Assay Genie empowers scientists with a powerful tool for elucidating the intricate mechanisms of immune cell function, paving the way for advancements in immunology research and personalized medicine.

Product Title:PE/Cyanine7 Anti-Human CD45RA Antibody [HI100]
SKU:AGEL0958
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI100
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE/Cyanine7 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

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