PE Anti-Human CD45RA Antibody [HI100] (AGEL0230)

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SKU:
AGEL0230
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
HI100
Conjugation:
PE
Applications:
FC
Frequently bought together:

Description

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PE Anti-Human CD45RA Antibody [HI100]

The Human CD45RA Monoclonal Antibody (PE Conjugated, HI100) offered by AssayGenie (AGEL0230) is a cutting-edge tool tailored for research in immunology and cell biology. This antibody is specifically designed to target CD45RA, a crucial cell surface marker associated with naïve T cells that play a pivotal role in the immune system's response.Developed for use in flow cytometry applications, this PE-conjugated monoclonal antibody provides high specificity and sensitivity in detecting CD45RA expression in human samples. The HI100 antibody is meticulously validated to ensure robust and reliable performance, making it an indispensable asset for investigating the role of CD45RA in immune responses, cellular differentiation, and disease pathogenesis.

By utilizing this advanced antibody, researchers can gain valuable insights into the function of CD45RA-positive cells, paving the way for groundbreaking discoveries in immunotherapy, autoimmune diseases, and infectious disorders. Stay at the forefront of scientific exploration with the Human CD45RA Monoclonal Antibody (PE Conjugated, HI100) from AssayGenie.

Product Title:PE Anti-Human CD45RA Antibody [HI100]
SKU:AGEL0230
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI100
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

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