The CD45RA Monoclonal Antibody (APC Conjugated, HI100) from AssayGenie (AGEL0231) is a cutting-edge tool for research involving CD45RA, a key cell surface marker associated with immune cell differentiation and activation. This antibody is specifically engineered for use with human samples, offering high specificity and sensitivity in flow cytometry and other applications.CD45RA, a member of the protein tyrosine phosphatase family, is involved in T-cell activation and differentiation, making it a crucial target for immunology and cellular biology studies. The HI100 antibody recognizes the CD45RA protein with exceptional precision, allowing researchers to accurately identify and analyze CD45RA-expressing cell populations in complex biological samples.
By utilizing the CD45RA Monoclonal Antibody (APC Conjugated, HI100), researchers can gain valuable insights into immune cell subsets, immune response dynamics, and the role of CD45RA in various disease states. This advanced reagent is essential for investigations spanning immunophenotyping, cell sorting, and functional assays, paving the way for discoveries in immunotherapy, infectious diseases, and autoimmunity research.Unlock the full potential of your research with the CD45RA Monoclonal Antibody (APC Conjugated, HI100) from AssayGenie. Empower your studies with accurate, reliable, and innovative tools designed to drive progress in the field of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08575
Gene ID:
5788
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.