APC Anti-Human CD45 Antibody [HI30] (AGEL1679)

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SKU:
AGEL1679
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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APC Anti-Human CD45 Antibody [HI30]

The Human CD45 Monoclonal Antibody (APC-Conjugated, HI30, AGEL1679) offered by AssayGenie is a valuable tool for researchers studying immune cell populations. This antibody specifically targets the CD45 protein, a key marker present on all leukocytes, making it an essential component in immunophenotyping experiments. The APC conjugation allows for easy and sensitive detection in flow cytometry applications, enabling precise identification and quantification of various immune cell subtypes.CD45, also known as leukocyte common antigen, plays a crucial role in immune response regulation and cell signaling. Its presence on all leukocytes makes it a valuable marker for distinguishing immune cell populations in complex mixtures.

By utilizing this APC-conjugated monoclonal antibody, researchers can accurately analyze immune cell distributions, track cell activation states, and monitor immune responses in different experimental settings.This CD45 Monoclonal Antibody is highly specific for human samples, ensuring reliable and reproducible results in diverse research applications. Whether investigating immune cell dynamics in cancer, infectious diseases, or autoimmune disorders, this antibody provides a robust tool for characterizing immune cell populations and understanding their roles in disease pathogenesis. Trust AssayGenie's CD45 Monoclonal Antibody for accurate and precise immunophenotyping studies in your research endeavors.

Product Title:APC Anti-Human CD45 Antibody [HI30]
SKU:AGEL1679
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI30
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

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