PE/Cyanine7 Anti-Human CD44 Antibody [Hermes-1] (AGEL2105)

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SKU:
AGEL2105
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
J110
Conjugation:
PE/Cy7
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD44 Antibody [Hermes-1]

The Human CD44 Monoclonal Antibody PE-Cyanine7 Conjugated (J110) (AGEL2105) is a valuable tool for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion, migration, and signaling processes. This antibody, engineered for specificity and sensitivity, is conjugated with PE-Cyanine7 for fluorescent detection applications, enabling easy visualization and analysis of CD44 expression in human samples. CD44 plays a crucial role in various biological processes, including lymphocyte activation, cell migration, and tumor metastasis.

Its expression has been linked to cancer progression and stem cell function, making it an important target for research in oncology and regenerative medicine.With its high reactivity and validated performance in flow cytometry and immunofluorescence assays, the Human CD44 Monoclonal Antibody PE-Cyanine7 Conjugated (J110) (AGEL2105) is an essential reagent for investigating the functional role of CD44 in health and disease, offering valuable insights for therapeutic development and clinical applications.

Product Title:PE/Cyanine7 Anti-Human CD44 Antibody [Hermes-1]
SKU:AGEL2105
Size:20 Tests, 100 Tests, 200 Tests
Clone No:Hermes-1
Synonyms:LHR;PGP-I;CDw44;Epican;HUTCH-I;
Host Species:Rat
Reactivity:Human
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16070
Gene ID:960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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