APC Anti-Human CD44 Antibody [Hermes-1] (AGEL2103)

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SKU:
AGEL2103
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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APC Anti-Human CD44 Antibody [Hermes-1]

The Human CD44 Monoclonal Antibody (APC Conjugated) J110 (AG2103) offered by AssayGenie is a specialized tool for researchers studying the CD44 protein, a cell surface glycoprotein involved in cell adhesion, migration, and signaling in various physiological and pathological processes. This monoclonal antibody, conjugated with allophycocyanin (APC), allows for sensitive detection and quantification of CD44 expression in human samples using flow cytometry and other fluorescence-based assays.CD44 is a multifunctional molecule known for its roles in cell-cell interactions, lymphocyte homing, and tumor metastasis. Its diverse isoforms and splicing variants contribute to its versatility in mediating cellular processes, making it a target of interest in cancer research, stem cell biology, and immunology.

The APC-conjugated J110 antibody specifically recognizes CD44, enabling precise analysis of its expression levels and localization in different cell types and tissues.With its high specificity and sensitivity, the Human CD44 Monoclonal Antibody (APC Conjugated) J110 (AG2103) from AssayGenie is a valuable tool for elucidating the functions of CD44 in health and disease contexts. Researchers can use this antibody to investigate the involvement of CD44 in processes such as cell adhesion, inflammation, and metastasis, paving the way for advancements in understanding and targeting CD44-related pathways in various research areas.

Product Title:APC Anti-Human CD44 Antibody [Hermes-1]
SKU:AGEL2103
Size:20 Tests, 100 Tests, 200 Tests
Clone No:Hermes-1
Synonyms:LHR;PGP-I;CDw44;Epican;HUTCH-I;
Host Species:Rat
Reactivity:Human
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16070
Gene ID:960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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