GenieFluor 647 Anti-Human CD44 Antibody [Hermes-1] (AGEL2107)

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SKU:
AGEL2107
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD44 Antibody [Hermes-1]

The Human CD44 Monoclonal Antibody (AF647 Conjugated) (J110) is a cutting-edge reagent offered by Assay Genie, specifically designed for research and analysis of the CD44 cell surface glycoprotein. This monoclonal antibody is conjugated with AF647, a fluorescent dye, allowing for precise imaging and detection in various experimental setups. It is engineered to exhibit high reactivity with human samples, providing reliable and accurate results in immunofluorescence and flow cytometry assays.CD44 is a versatile cell adhesion molecule known for its involvement in numerous biological processes, including cell-cell interactions, migration, and signaling pathways. Its diverse functions make it a key player in cancer progression, stem cell biology, and inflammatory responses. By targeting CD44, researchers can gain insights into tumor development, metastasis, and the potential therapeutic opportunities for cancer treatment.

The Human CD44 Monoclonal Antibody (AF647 Conjugated) (J110) serves as a valuable tool for investigating the role of CD44 in health and disease, offering a reliable means to study its expression and localization in a wide range of cell types and tissues.This antibody is an essential component for scientists and researchers interested in delving deeper into the functions of CD44 and its implications in various physiological and pathological conditions. With its advanced technology and proven specificity, the Human CD44 Monoclonal Antibody (AF647 Conjugated) (J110) from Assay Genie enables precise and comprehensive analysis of CD44, paving the way for groundbreaking discoveries in the fields of immunology, oncology, and cellular biology.

Product Title:GenieFluor 647 Anti-Human CD44 Antibody [Hermes-1]
SKU:AGEL2107
Size:20 Tests, 100 Tests, 200 Tests
Clone No:Hermes-1
Synonyms:LHR;PGP-I;CDw44;Epican;HUTCH-I;
Host Species:Rat
Reactivity:Human
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16070
Gene ID:960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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