PerCP/Cyanine5.5 Anti-Human CD41 Antibody [HIP8] (AGEL1137)

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SKU:
AGEL1137
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Human CD41 Antibody [HIP8]

The Human CD41 Monoclonal Antibody (PERCP-CY5.5) - HIP8 (AGL1137) is a powerful tool for researchers investigating CD41, a cell surface glycoprotein that plays a critical role in platelet function and blood coagulation. This monoclonal antibody, conjugated with PERCP-CY5.5 for enhanced detection, offers high specificity and sensitivity in identifying CD41 in human samples.CD41, also known as integrin alpha IIb, is essential for platelet aggregation and clot formation, making it a key player in hemostasis and thrombosis. By targeting CD41 with this antibody, researchers can study its expression and function in various cell types, shedding light on its involvement in blood disorders, cardiovascular diseases, and thrombotic events.

With its validated performance in flow cytometry and other applications, the Human CD41 Monoclonal Antibody (PERCP-CY5.5) - HIP8 (AGL1137) is a valuable asset for investigations in hematology, vascular biology, and related fields. By enabling precise detection and analysis of CD41, this antibody supports research aimed at understanding the mechanisms underlying platelet activation and coagulation processes, paving the way for advancements in diagnostic and therapeutic strategies for blood-related disorders.

Product Title:PerCP/Cyanine5.5 Anti-Human CD41 Antibody [HIP8]
SKU:AGEL1137
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIP8
Synonyms:Integrin alpha-Iib;ITGA2B;GPalpha Iib;GPIIb;Platelet membrane glycoprotein Iib;CD41;GP2B; ITGAB;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08514
Gene ID:3674
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

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