PE/Cyanine7 Anti-Human CD41 Antibody [HIP8] (AGEL1135)

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SKU:
AGEL1135
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
HIP8
Conjugation:
PE/Cy7
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD41 Antibody [HIP8]

The Human CD41 Monoclonal Antibody PE-Cyanine7 Conjugated (HIP8/AGEL1135) is a cutting-edge tool for researchers studying CD41, a crucial cell surface molecule involved in platelet function and blood clotting. This monoclonal antibody, meticulously developed through rigorous procedures, offers exceptional specificity and sensitivity in detecting CD41 in human samples. With its PE-Cyanine7 conjugation, it facilitates bright and distinct fluorescence signals in flow cytometry and other fluorescence-based applications.CD41, also known as integrin alpha IIb, plays a pivotal role in hemostasis and thrombosis by mediating platelet aggregation and adhesion to injured blood vessels. Its dysregulation is associated with bleeding disorders, thrombotic diseases, and cardiovascular complications, warranting detailed investigation in biomedical research.

By targeting CD41 with this advanced antibody, researchers can gain valuable insights into platelet biology, vascular health, and therapeutic strategies for managing related disorders.The Human CD41 Monoclonal Antibody PE-Cyanine7 Conjugated (HIP8/AGEL1135) is a versatile tool for elucidating the functions and molecular mechanisms of CD41 in various experimental settings, ranging from basic platelet biology studies to clinical investigations of cardiovascular diseases and thrombosis. Its high specificity, sensitivity, and compatibility with diverse research techniques make it an indispensable resource for scientists aiming to deepen their understanding of CD41 and its implications in health and disease.

Product Title:PE/Cyanine7 Anti-Human CD41 Antibody [HIP8]
SKU:AGEL1135
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIP8
Synonyms:Integrin alpha-Iib;ITGA2B;GPalpha Iib;GPIIb;Platelet membrane glycoprotein Iib;CD41;GP2B; ITGAB;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08514
Gene ID:3674
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

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