PE/Cyanine5 Anti-Human CD41 Antibody [HIP8] (AGEL1134)

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SKU:
AGEL1134
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD41 Antibody [HIP8]

The Human CD41 Monoclonal Antibody (PE/Cyanine5 Conjugated) (HIP8/AGEL1134) is a specialized research tool designed for the detection and analysis of CD41, also known as integrin alpha IIb, a crucial protein involved in platelet function and clot formation. This antibody, conjugated with PE/Cyanine5, offers high sensitivity and specificity when used in flow cytometry applications, allowing for the precise identification of CD41-expressing cells in human samples.CD41 is a key player in hemostasis and thrombosis, making it a target of interest in various research areas such as cardiovascular diseases, hematologic disorders, and platelet-related pathologies.

By targeting CD41 with this monoclonal antibody, researchers can gain insights into the expression patterns and functions of this important protein in different cell types and disease conditions.The reliable performance and reproducibility of this antibody in flow cytometry experiments make it an essential tool for studies focused on understanding the role of CD41 in health and disease. Its ability to specifically bind to CD41 on the cell surface enables researchers to explore potential therapeutic strategies targeting this protein for the management of thrombotic disorders and other related conditions.

Product Title:PE/Cyanine5 Anti-Human CD41 Antibody [HIP8]
SKU:AGEL1134
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIP8
Synonyms:Integrin alpha-Iib;ITGA2B;GPalpha Iib;GPIIb;Platelet membrane glycoprotein Iib;CD41;GP2B; ITGAB;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08514
Gene ID:3674
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

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