The Human CD41 Monoclonal Antibody (FITC Conjugated) - HIP8 (AGEL0326) offered by AssayGenie is a cutting-edge tool designed for research applications involving CD41, a key cell surface antigen involved in platelet function and thrombosis. This monoclonal antibody, labeled with FITC for fluorescent detection, is specifically tailored for use with human samples and is validated for various immunofluorescence and flow cytometry assays.CD41, also known as glycoprotein IIb/IIIa, is an essential component of platelet function and plays a crucial role in blood clotting and hemostasis. The Human CD41 Monoclonal Antibody enables precise detection and visualization of CD41 expression on cell surfaces, allowing for detailed analysis and characterization in a range of experimental settings.
Its high specificity and sensitivity make it an indispensable tool for researchers studying platelet biology, thrombotic disorders, and related conditions.By targeting CD41 with this monoclonal antibody, researchers can gain valuable insights into platelet function, thrombus formation, and the molecular mechanisms underlying coagulation processes. This antibody opens up new possibilities for investigating disorders such as thrombocytopenia, clotting disorders, and cardiovascular diseases, ultimately contributing to advancements in diagnostics, therapeutics, and biomedical research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08514
Gene ID:
3674
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.