GenieFluor 647 Anti-Human CD41 Antibody [HIP8] (AGEL1138)

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SKU:
AGEL1138
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD41 Antibody [HIP8]

The Human CD41 Monoclonal Antibody (AF647 Conjugated) - HIP8 (AGEL1138) is a cutting-edge tool for investigators studying CD41, a pivotal cell surface molecule with key roles in hemostasis and thrombosis. This monoclonal antibody, expertly conjugated with AF647 for enhanced detection capabilities, offers exceptional specificity and sensitivity in detecting CD41 in human samples. Its efficacy in various applications, including flow cytometry and immunofluorescence, makes it an invaluable asset for researchers exploring platelet biology, clotting disorders, and cardiovascular diseases.CD41, also known as integrin alpha IIb, serves as a crucial receptor on platelets, facilitating their aggregation during the clotting process.

By targeting CD41 with precision, researchers can delve deeper into the mechanisms underlying thrombotic events, thrombocytopenia, and other platelet-related disorders. Unraveling the intricacies of CD41 function is vital for advancing our understanding of cardiovascular health and developing novel therapeutic strategies to manage thrombotic complications effectively.Enhance your research endeavors in hematology, cardiology, and vascular biology with the Human CD41 Monoclonal Antibody (AF647 Conjugated) - HIP8 (AGEL1138). Unlock new insights into platelet biology and thrombosis, paving the way for innovative approaches to prevent and treat thrombotic disorders.

Product Title:GenieFluor 647 Anti-Human CD41 Antibody [HIP8]
SKU:AGEL1138
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIP8
Synonyms:Integrin alpha-Iib;ITGA2B;GPalpha Iib;GPIIb;Platelet membrane glycoprotein Iib;CD41;GP2B; ITGAB;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08514
Gene ID:3674
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

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