The Human CD40 Monoclonal Antibody PE-Cyanine5 Conjugated (G28-5) AGEL2097 is a powerful tool for researchers studying CD40, a cell surface protein involved in immune responses and inflammation modulation. This monoclonal antibody, conjugated with PE-Cyanine5, offers high specificity and sensitivity for detecting CD40 in human samples, making it ideal for flow cytometry and immunofluorescence applications.CD40 is known for its crucial role in immune cell activation and regulation. By targeting CD40 with this monoclonal antibody, researchers can gain insights into the signaling pathways and interactions involving CD40, which are essential for understanding immune system function and developing targeted therapies for conditions such as autoimmune diseases, infectious diseases, and cancer.
With its high reactivity and specificity, the Human CD40 Monoclonal Antibody PE-Cyanine5 Conjugated (G28-5) AGEL2097 provides a reliable tool for investigating the role of CD40 in various cellular processes, making it a valuable asset for immunology and cancer research studies.
Product Title:
PE/Cyanine5 Anti-Human CD40 Antibody [G28.5]
SKU:
AGEL2097
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
G28.5
Synonyms:
Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P25942
Gene ID:
958
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).