APC Anti-Human CD40 Antibody [G28.5] (AGEL2096)

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SKU:
AGEL2096
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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APC Anti-Human CD40 Antibody [G28.5]

The Human CD40 Monoclonal Antibody (APC Conjugated) G28-5 (AGEL2096) is a powerful tool for researchers studying CD40, a cell surface protein involved in immune responses and cell signaling. This monoclonal antibody is specifically designed for use in flow cytometry applications, allowing for the precise detection and analysis of CD40 expression in human samples.CD40 is a crucial regulator of immune responses, functioning to activate immune cells and promote various immune functions. Its role in immune regulation and cell communication makes it a key target for research in immunology, inflammation, and autoimmune diseases. By using the APC-conjugated G28-5 antibody, researchers can effectively study CD40 expression patterns in different cell types, providing valuable insights into its functions and potential therapeutic implications.

With its high specificity and sensitivity, the G28-5 antibody offers reliable and reproducible results, making it an essential tool for investigations into CD40-mediated immune responses and related pathways. Whether studying immune cell activation, immunotherapy development, or inflammatory processes, this monoclonal antibody is a valuable asset for advancing research in the fields of immunology and cancer biology.

Product Title:APC Anti-Human CD40 Antibody [G28.5]
SKU:AGEL2096
Size:20 Tests, 100 Tests, 200 Tests
Clone No:G28.5
Synonyms:Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25942
Gene ID:958
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).

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