The Human CD4 Monoclonal Antibody - PE/Cyanine7 Conjugated (RPA-T4) is a cutting-edge tool for immunology research, designed to target the CD4 protein on human cells. This monoclonal antibody is conjugated with PE/Cyanine7 for fluorescent detection, allowing for precise and effective analysis of CD4 expression in various cell types. The CD4 protein is a crucial marker for T helper cells, playing a key role in the immune response and regulation of immune functions. By specifically binding to CD4, this antibody enables researchers to study the distribution and function of CD4-positive cells in both healthy and diseased tissues.
With its high reactivity and specificity for human samples, the CD4 Monoclonal Antibody - PE/Cyanine7 Conjugated (RPA-T4) is a valuable resource for studies focused on immune cell identification, profiling, and characterization. Whether investigating immune disorders, infectious diseases, or immune responses in cancer, this antibody provides researchers with a powerful tool for advancing their understanding of the immune system.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).