The Human CD4 Monoclonal Antibody (PE-Cyanine5.5 Conjugated) (RPA-T4) is an essential tool for researchers studying the CD4 protein, a key player in the immune system's response. This monoclonal antibody, conjugated with PE-Cyanine5.5, allows for precise detection and analysis of CD4 in human samples, opening up new avenues for immunology and cancer research.CD4, also known as T-helper cells, plays a crucial role in coordinating immune responses and is a primary target for HIV infection. By targeting the CD4 protein with this specialized antibody, researchers can gain valuable insights into immune function and disease progression.
The high specificity and sensitivity of this antibody make it an invaluable tool for studying CD4-related mechanisms in various cell types.Whether investigating autoimmune disorders, infectious diseases, or cancer immunotherapy, the Human CD4 Monoclonal Antibody (PE-Cyanine5.5 Conjugated) (RPA-T4) provides researchers with a reliable and effective way to advance their understanding of CD4 biology. Its validated performance in flow cytometry and other applications makes it a versatile choice for a wide range of research projects focused on immune system function.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).