The Human CD4 Monoclonal Antibody (PE/Cy5 Conjugated) RPA-T4 (AGEL0403) is a cutting-edge tool for immunological research. Specifically designed for the detection and analysis of the CD4 cell surface protein, this antibody is a crucial component in studying immune responses.CD4, a key player in the immune system, is essential for coordinating immune responses and is primarily found on helper T cells. The monoclonal antibody AGEL0403 is conjugated with PE/Cy5, allowing for fluorescence-based analysis and enabling precise visualization and quantification of CD4-expressing cells.This monoclonal antibody is rigorously validated for use in flow cytometry and immunofluorescence, providing accurate and reliable results in a variety of experimental settings.
By targeting CD4, researchers can gain insights into immune function, autoimmune diseases, infectious diseases, and immunodeficiency conditions, paving the way for advancements in immunotherapy and precision medicine.Whether studying T cell activation, viral infections, or immunological disorders, the Human CD4 Monoclonal Antibody (PE/Cy5 Conjugated) RPA-T4 (AGEL0403) is an indispensable tool for researchers looking to unravel the complexities of the immune system and develop novel therapeutic strategies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).