The Human CD4 Monoclonal Antibody (APC-Conjugated) RPA-T4 (AGEL0401) offered by AssayGenie is a premium product designed for precise and specific detection of CD4, a crucial cell surface marker involved in immune function. This monoclonal antibody is conjugated with APC for enhanced signal intensity and is optimized for flow cytometry applications, enabling accurate identification and analysis of CD4-expressing cells in human samples.CD4, also known as T-helper cells, plays a pivotal role in orchestrating immune responses by coordinating the activities of other immune cells. Its expression on the cell surface serves as a key indicator of immune system status and functionality.
The CD4 Monoclonal Antibody (APC-Conjugated) RPA-T4 (AGEL0401) allows researchers to investigate CD4 distribution, quantify cell populations, and study immune responses in a variety of experimental settings, including immunology, infectious diseases, and autoimmune disorders.By leveraging the specificity and sensitivity of this antibody, researchers can advance their understanding of immune mechanisms, disease pathology, and therapeutic interventions. With its reliable performance and broad utility, the CD4 Monoclonal Antibody (APC-Conjugated) RPA-T4 (AGEL0401) from AssayGenie is an essential tool for cutting-edge research in immunology and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01730
Gene ID:
920
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).