The Human CD36 Monoclonal Antibody FITC Conjugated (5-271) (AGEL1822) is a specialized tool for research involving CD36, a cell surface receptor with diverse functions in lipid metabolism, inflammation, and atherosclerosis. This monoclonal antibody, labeled with FITC for fluorescence detection, is specifically designed for use in flow cytometry and immunofluorescence applications.CD36, also known as scavenger receptor B2, is a multifunctional receptor involved in various cellular processes, including lipid uptake, innate immune response modulation, and inflammation regulation. Its role in lipid metabolism and atherogenesis makes it a target of interest in studies related to cardiovascular diseases, metabolic disorders, and inflammatory conditions.The FITC-conjugated CD36 monoclonal antibody (5-271) provides researchers with a reliable tool for identifying and quantifying CD36 expression in different cell types and tissues.
Its fluorescence properties enable visualization and analysis of CD36 localization and levels, making it a valuable asset in research exploring the functions and implications of CD36 in health and disease.With its high specificity and sensitivity, this CD36 monoclonal antibody is a valuable resource for investigators seeking to advance their understanding of CD36 biology and its potential implications in various pathophysiological processes. Whether investigating lipid metabolism, inflammatory responses, or cardiovascular health, this antibody offers precise and reliable detection of CD36, facilitating insightful research outcomes in diverse fields such as cardiovascular biology, metabolism, and immunology.
Product Title:
FITC Anti-Human CD36 Antibody [5-271]
SKU:
AGEL1822
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
5-271
Synonyms:
GP3B;GP4;GPIV;GPIIIB;PAS-4;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16671
Gene ID:
948
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD36 is an 85 kD integral membrane glycoprotein, also known as GPIIIb, or GPIV. It is expressed on various epithelial and endothelial cells as well as erythrocytes, platelets, macrophages/monocytes and some macrophage-derived dendritic cells. CD36 functions as a scavenger receptor, binding thrombospondin, long chain fatty acids, oxidized LDL, collagen type I, IV, and V as well as apoptotic cells. The 5-271 antibody has been reported to be useful for flow cytometry.
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