PE/Cyanine7 Anti-Human CD35 Antibody [E11] (AGEL1014)

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SKU:
AGEL1014
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
E11
Conjugation:
PE/Cy7
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD35 Antibody [E11]

The Human CD35 Monoclonal Antibody PE-Cyanine7 Conjugated, E11 (AGEL1014) offered by AssayGenie is a valuable tool for researchers studying CD35, a cell surface receptor involved in immune response modulation. This monoclonal antibody, conjugated with PE-Cyanine7, is specifically designed for use in flow cytometry applications, allowing for the detection and analysis of CD35 expression in human samples.CD35, also known as complement receptor 1 (CR1), plays a crucial role in the regulation of the complement system, which is a key component of the innate immune response. By binding to complement components, CD35 helps to prevent excessive immune activation and maintains immune homeostasis. Research into CD35 function is essential for understanding its role in various immune-related diseases, including autoimmune disorders, infectious diseases, and inflammatory conditions.

The Human CD35 Monoclonal Antibody PE-Cyanine7 Conjugated, E11 (AGEL1014) provides high specificity and sensitivity in detecting CD35 expression, making it an ideal tool for investigations in immunology, infectious diseases, and autoimmunity. Researchers can use this antibody to study the role of CD35 in immune regulation and explore its potential as a therapeutic target for manipulating immune responses in various disease settings. Unlock the potential of CD35 research with this reliable and versatile antibody from AssayGenie.

Product Title:PE/Cyanine7 Anti-Human CD35 Antibody [E11]
SKU:AGEL1014
Size:20 Tests, 100 Tests, 200 Tests
Clone No:E11
Synonyms:Complement receptor type 1;CR1;C3b/C4b receptor;CD35;CR1;C3BR;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P17927
Gene ID:1378
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

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