Purified Anti-Human CD35 Antibody [E11] (AGEL0257)

(No reviews yet) Write a Review
SKU:
AGEL0257
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
E11
Conjugation:
Unconjugated
Applications:
FC
IHC
IP
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Purified Anti-Human CD35 Antibody [E11]

The Human CD35 Monoclonal Antibody (E11) is a valuable tool for researchers studying CD35, a cell surface receptor known for its role in the immune system, particularly in the recognition and clearance of pathogens and damaged cells. This monoclonal antibody, clone E11, specifically targets the CD35 protein in human samples, providing a reliable means of detecting and analyzing CD35 expression in various cell types and tissues.CD35, also known as complement receptor type 1 (CR1), is a key player in the innate immune response, serving as a receptor for complement proteins and facilitating phagocytosis and clearance of immune complexes. Its involvement in immune regulation and host defense mechanisms makes CD35 a critical target for studies in immunology, infectious diseases, and autoimmune disorders.

The ability to accurately detect and quantify CD35 expression using the E11 monoclonal antibody opens up avenues for understanding its function in health and disease.Researchers can utilize the Human CD35 Monoclonal Antibody (E11) in techniques such as immunohistochemistry, flow cytometry, and immunofluorescence to investigate the expression patterns and localization of CD35 in biological samples. With its high specificity and sensitivity, this antibody provides a robust tool for exploring the diverse roles of CD35 in immune responses and pathophysiological conditions. Whether studying immune interactions, inflammation, or host-pathogen interactions, the E11 monoclonal antibody offers a versatile solution for elucidating the functions of CD35 in various research settings.

Product Title:Purified Anti-Human CD35 Antibody [E11]
SKU:AGEL0257
Size:25µg, 100µg
Clone No:E11
Synonyms:Complement receptor type 1;CR1;C3b/C4b receptor;CD35;CR1;C3BR;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P17927
Gene ID:1378
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

0 Reviews

View AllClose

Related Products